NR vs NMN vs Nicotinamide for Glaucoma: Which NAD+ Booster Has the Strongest Evidence?
Current research has focused on three NAD precursors: nicotinamide (vitamin Bâ), nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN)....
Deep research and expert guides on maintaining your visual health.
Current research has focused on three NAD precursors: nicotinamide (vitamin Bâ), nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN)....
Endothelin-1 (ET-1) is made by cells lining blood vessels throughout the body, and it helps regulate normal blood pressure and flow. In the eye, ET-1...
A nationwide Danish registry study also found that GLP-1 agonist use was linked to a lower glaucoma risk. Compared to diabetic patients on other...
In a rabbit glaucoma model (pressure raised by a gel in the eye), researchers injected NGF around the eye (retrobulbar) before damage. Those rabbits...
ET-1 is produced by many eye tissues (retina, ciliary body, trabecular meshwork, etc.). It normally helps regulate blood flow and aqueous humor...
In 2015, researchers discovered MOTS-c â a 16-amino-acid peptide encoded in mitochondrial DNA (mtDNA) (). It is produced from a short open reading...
Even if you load up on pyruvate, an inactive body wonât convert it to extra ATP unless itâs needed. Instead, the surplus pyruvate enters normal...
What the study found: A new research report suggests that tiny leaks in tiny blood vessels in the eye may contribute to glaucoma damage. In simple...
One new idea is that damage to small retinal blood vessels might contribute to glaucoma. Normally, the tiny blood vessels in the retina have tight...
The April 2026 trials can be grouped by their main intervention modality:
Earlier trial results. A recent Phase III study (NCX 470) and others confirmed that combined outflow enhancers can beat traditional drops. For...
Capturing slow changes in eye pressure and fields (monitoring). A recent study (the ADAGES group) looked at long-term glaucoma data and found that...
For example, imagine a treatment that boosts the survival of optic nerve fibers or blocks harmful chemical processes in the nerve. If such a...
Even in cases like age-related macular degeneration or diabetic retinopathy, the optic nerve often stays healthy, so restoring vision means fixing or...
Recent work (for example, Andrej Karpathyâs âautoresearchâ project () ()) suggests that AI agents can autonomously run hundreds of small experiments...
Researchers are exploring new ways to one day fix this problem by replacing or protecting those lost nerve cells. One exciting idea is to transplant...
The NT-501 implant is a small capsule (about 1Ă6 mm) that a surgeon places inside the eye (in the gel-like vitreous near the retina) during a minor...
There is no single answer to âhow fast does glaucoma progress?â â rates vary enormously. Major studies show untreated glaucoma often worsens...
Our visual field test is inspired by the perimetry methods eye care professionals use. Check for blind spots and track changes over time.
Test Your VisionNeuroprotection refers to strategies and treatments meant to protect nerve cells from damage, slow their degeneration, or help them recover after injury. In the context of the eye, it means trying to keep retinal ganglion cells and the optic nerve healthy so vision is preserved even when other risk factors, like eye pressure, are present. Approaches to neuroprotection include drugs that reduce harmful chemical reactions, improve energy production in cells, reduce inflammation, or boost blood flow and oxygen delivery to nerve tissue. Lifestyle measures, such as good cardiovascular health, healthy diet, and avoiding smoking, also support nerve health. Scientists are testing many ideas for neuroprotection, from medications and nutritional supplements to devices and gene therapies, but evidence varies and research is ongoing. Neuroprotection matters because once nerve cells are lost, they do not regrow easily, so preventing damage is often the best way to preserve function. In conditions where standard treatments do not fully stop progression, adding neuroprotective strategies could help maintain vision or slow decline. Discussing neuroprotection with a healthcare provider can help people understand realistic expectations and available options for protecting nerve health.