From Bench to Bedside: Translating Longevity Pathways to Glaucoma Supplements
Biologists studying aging (“longevity pathways”) have identified key regulators – AMPK, mTOR, sirtuins, autophagy, and cellular senescence – that...
Eye Care Insights
Deep research and expert guides on maintaining your visual health.
Omega-3 Fatty Acids, Inflammation Resolution, and Glaucoma Progression
Not all trials find benefit. Some case series and a controlled study in normal-tension glaucoma showed no improvement in visual fields or nerve layer...
Citicoline (CDP-Choline) for Visual Pathway Support and Cognitive Aging
Citicoline (cytidine-5′-diphosphocholine) is metabolized into cytidine and choline in the body. Choline feeds into the synthesis of...
Alpha-Lipoic Acid: Redox Modulation and Neurovascular Support in Glaucoma
Alpha-lipoic acid (ALA), also known as thioctic acid, is a short-chain sulfur-containing fatty acid synthesized in mitochondria. In its reduced form...
Creatine and Energy Buffering in Retinal and Optic Nerve Tissues
Importantly, this system exists not only in muscle but in nerve cells. Neurons (including RGCs) express CK isoforms that enable them to use creatine....
Designing Multi-Ingredient Neuroprotective Formulations for Glaucoma
However, combining many compounds also has pitfalls. Overlapping mechanisms can lead to diminishing returns. The so-called “antioxidant paradox”...
Astaxanthin for Oxidative Stress and Ocular Blood Flow
Astaxanthin protects eye cells from oxidative damage. In animal models of eye disease, AXT reduced markers of stress and inflammation in the retina...
B Vitamins, Homocysteine, and Vascular Dysregulation in Glaucoma
Research suggests that homocysteine-related vascular damage is relevant to glaucoma. For example, animal models of glaucoma show retinal metabolic...
Ginkgo biloba for Ocular Perfusion and Visual Field Preservation: Promise and Precautions
By contrast, larger reviews find no clear benefit on field metrics. A 2025 systematic review of 8 trials (428 subjects) concluded that GBE did not...
Coenzyme Q10 as a Mitochondrial Adjunct in Glaucoma and Lifespan Health
Notably, in the topical CoQ10 trial (), all eyes were also on standard drugs (timolol/dorzolamide), and CoQ10-treated eyes fared better. Thus, CoQ10...
Nicotinamide and NAD+ Boosting for Glaucoma Neuroprotection and Healthy Aging
NAD<sup>+</sup> is a ubiquitous coenzyme that facilitates ATP production via glycolysis and oxidative phosphorylation, and serves as a substrate for...
Tele-Glaucoma and Home Monitoring in Aging Populations
Intraocular pressure (IOP) is the most important modifiable risk factor in glaucoma. Remote IOP monitoring lets patients record pressures at home...