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Biomarkers

Deep research and expert guides on maintaining your visual health.

IGF-1, mTOR Signaling, and Neurodegeneration Across Eye and Brain

IGF-1, mTOR Signaling, and Neurodegeneration Across Eye and Brain

Introduction Glaucoma is now recognized not just as an eye pressure problem but as a neurodegenerative disease of the optic nerve. Retinal ganglion cells (RGCs) – the neurons that send visual signals from eye to brain – degenerate in glaucoma, much like neurons die in Alzheimer’s or Parkinson’s disease (pmc.ncbi.nlm.nih.gov) (pmc.ncbi.nlm.nih.gov). Researchers are uncovering how general health...

Oxidative Stress Biomarkers, HRV, and Retinal Ganglion Cell Loss

Oxidative Stress Biomarkers, HRV, and Retinal Ganglion Cell Loss

Introduction Glaucoma is an eye disease in which retinal ganglion cells (RGCs) – the nerve cells that carry visual signals from the eye to the brain – slowly die. This causes gradual, irreversible vision loss. Doctors usually focus on lowering eye pressure to slow glaucoma, but research now shows that oxidative stress (a kind of chemical stress in the body) and imbalances in the autonomic nervou...

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biomarkers

Biomarkers are measurable signs that reveal information about how the body is functioning. They can be molecules in blood or urine, cells, images from scans, or simple measurements like blood pressure and heart rate. Clinicians and researchers use biomarkers to detect disease, monitor how it is progressing, or see whether a treatment is working. Some markers show risk before symptoms appear, others confirm a diagnosis, and some predict how well a person will respond to a particular therapy. Biomarkers matter because they make it possible to diagnose conditions earlier, tailor treatments to individuals, and track recovery without invasive procedures. Examples include blood sugar for diabetes, cholesterol for heart disease, and specific proteins or genetic features for certain cancers. A useful biomarker must be reliable, repeatable, and validated in many people, because values can vary with age, activity, or other conditions. That variability is why professionals interpret biomarkers alongside symptoms and other tests rather than relying on any single measure.