Endothelin-1 Peptide and Glaucoma: Targeting a Problem Pathway
Endothelin-1 (ET-1) is made by cells lining blood vessels throughout the body, and it helps regulate normal blood pressure and flow. In the eye, ET-1...
Deep research and expert guides on maintaining your visual health.
Endothelin-1 (ET-1) is made by cells lining blood vessels throughout the body, and it helps regulate normal blood pressure and flow. In the eye, ET-1...
Our visual field test is inspired by the perimetry methods eye care professionals use. Check for blind spots and track changes over time.
Test Your VisionVasoconstriction is the narrowing of blood vessels that happens when the smooth muscle in their walls tightens. This tightening reduces the space through which blood can flow, so less blood gets past that point. It is a normal body response used to control blood pressure and to conserve heat when the environment is cold. The nervous system and several chemical messengers tell vessels when to tighten and when to relax. Substances such as adrenaline, angiotensin, and endothelin commonly trigger this response, while other signals cause relaxation. In short bursts it is helpful โ for example, it redirects blood to vital organs during stress or injury. But if vessels stay narrowed too long, or if they tighten in the wrong place, tissues can be starved of oxygen and nutrients. That can lead to problems like high blood pressure, pain from poor circulation, organ damage, or worsening of chronic diseases.