Deep research and expert guides on maintaining your visual health.
Neuroprotection Beyond Pressure: What’s Real, What’s Hype Glaucoma causes vision loss by damaging the optic nerve, often linked to high intraocular pressure (IOP) in the eye. Lowering IOP with drops or surgery is currently the only proven way to slow glaucoma’s progression (pmc.ncbi.nlm.nih.gov). However, many patients still lose vision despite good pressure control, so doctors are studying pres...
A clinical endpoint is a specific, measurable event or outcome that doctors and researchers use to decide whether a medical treatment works. It can be something obvious like living longer, having fewer symptoms, or needing less medicine, or it can be a lab measurement such as a change in blood pressure or a biological marker. Endpoints can be primary (the main question a study aims to answer) or secondary (additional effects the study also tracks). Some endpoints are direct and meaningful to patients, like improved vision or reduced pain, while others are surrogate measures that stand in for real benefit, for example a lab test that predicts future health. Because endpoints must be measurable, studies choose them carefully before the research starts so the results are clear and trustworthy. Clinical endpoints matter because they determine whether a treatment is considered effective and safe. Regulators, doctors, and patients rely on them to approve new drugs, decide on treatment plans, and weigh risks versus benefits. The choice of endpoint affects how long a study must run, how many people need to enroll, and how convincing the results will be. A study that uses a surrogate endpoint may be faster and cheaper, but its results sometimes do not translate into real-world improvement for patients. Clear, meaningful endpoints help ensure that medical advances actually improve health and quality of life, and they guide doctors in making better decisions for the people they care for.
