Bdnf

BDNF

BDNF stands for brain-derived neurotrophic factor and is a protein that helps nerve cells survive and work well. It is produced by neurons and other cells in the brain and retina and acts like a growth and support signal for neurons. BDNF helps nerve cells form and strengthen connections, a process that underlies learning, memory, and how we sense the world. When cells are stressed or injured, BDNF can encourage repair, reduce cell death, and promote regrowth of nerve fibers. Lower levels of BDNF have been linked to worse outcomes in various nerve-related conditions and loss of function in affected tissues. Researchers are interested in ways to boost BDNF using medicines, gene-based approaches, or lifestyle measures such as exercise. In practical terms, BDNF matters because it is a natural rescue and maintenance signal for neurons and can influence how well nervous system tissues stay healthy over time. Treatments that raise BDNF or mimic its action could help slow or reverse nerve damage and improve recovery, but delivering it safely and effectively is challenging. That makes it a major focus of ongoing research and a useful way to understand why some therapies or behaviors protect nerve function. Knowing about BDNF helps explain the biology behind many approaches aimed at preserving or restoring nervous system health.