Spermidine
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Spermidine is a small organic molecule called a polyamine that is naturally found in every cell of the body and in many foods. It plays multiple roles inside cells, including helping stabilize DNA, supporting cell growth, and regulating how cells recycle damaged parts. One of its best-known effects is stimulating autophagy, the process cells use to clear out old or faulty components and renew themselves. Autophagy is important for long-term cellular health, and boosting this process has been linked to slower aging and better function in organs such as the brain and the eye. Because of these effects, spermidine has attracted attention as a potential nutrient for healthy aging and protection against degenerative changes. You can get spermidine from foods like wheat germ, soy products, mature cheeses, and some fermented vegetables, and it is also available as a dietary supplement. Early studies in animals and cells show benefits for lifespan and organ health, but human research is still developing and does not yet provide definitive guidelines for use. Like any supplement, spermidine may interact with medications or have side effects in some people, so itâs wise to discuss it with a healthcare provider before starting it. Overall, spermidine supports a natural cellular clean-up process that seems linked to resilience during aging, making it a promising subject for further research and cautious practical use.