Metformin, rapamycin és geroscience gyógyszerek: Szemészeti eredmények
A metformin egy széles körben alkalmazott cukorbetegség-gyógyszer, amely aktiválja az AMP-aktivált kinázt (AMPK), utánozza a kalóriamegvonást, és...
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A metformin egy széles körben alkalmazott cukorbetegség-gyógyszer, amely aktiválja az AMP-aktivált kinázt (AMPK), utánozza a kalóriamegvonást, és...
Metformin Àr ett flitigt anvÀnt diabeteslÀkemedel som också aktiverar AMP-aktiverat kinas (AMPK), efterliknar kalorirestriktion och kan minska...
La metformine est un médicament largement utilisé contre le diabÚte qui active également la kinase activée par l'AMP (AMPK), imite la restriction...
Metformiin on laialdaselt kasutatav diabeediravim, mis aktiveerib ka AMP-aktiveeritud kinaasi (AMPK), imiteerib kaloripiirangut ja võib vÀhendada...
Metformin is a widely used diabetes medication that also activates AMP-activated kinase (AMPK), mimics calorie restriction, and can reduce cellular...
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ä»ãããã¹ããéå§Geroscience is a field of research that focuses on why aging increases the risk for many different diseases and how we might slow those underlying processes. Instead of treating each condition separately, researchers in this area study the common biological changes that happen with ageâlike chronic inflammation, reduced repair capacity, and the accumulation of damaged cellsâthat drive heart disease, dementia, diabetes and more. The goal is to find ways to delay those core changes so people stay healthier longer, possibly preventing several age-related illnesses at once. This approach shifts the emphasis from adding years to life to adding healthy years, often called improving "healthspan." Scientists in this field use studies in cells, animals, and people to test interventions that target fundamental aging processes, from drugs to lifestyle changes. The work has practical importance because aging is the biggest risk factor for the diseases that most often lead to disability and high health care costs. Geroscience also raises social and ethical questions about access, fairness, and how to use such therapies responsibly. Ultimately, the field aims to translate lab discoveries into real-world treatments that help people remain active and independent as they get older. For the average person, geroscience offers hope that future strategies could reduce the burden of multiple illnesses instead of managing them one by one.