Personalized Nutrition in Glaucoma: Nutrigenomic Interactions with Macronutrient Metabolism
APOE (Apolipoprotein E) – This gene makes a protein that transports cholesterol and fats in the body, especially in the brain and retina (). There...
Ppar
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PPAR
PPAR refers to a group of proteins called peroxisome proliferator-activated receptors, which act like switches inside cells to turn certain genes on or off. These proteins sit in the cell’s nucleus and respond to natural fat-derived molecules and some medicines, then change the activity of genes that control how the body uses and stores energy. There are several kinds of PPARs (often named alpha, gamma, and delta), and each one has a slightly different role: some help burn fats for fuel, others help store fat or regulate how cells respond to insulin. PPARs matter because they help balance energy use, inflammation, and metabolism across the body. Drugs that target PPARs are used to treat conditions like high blood lipids and diabetes, and natural changes in PPAR activity influence how people respond to different diets and fats. Because they regulate many genes, PPARs link what we eat to how efficiently our bodies turn food into energy and how tissues like liver, muscle, and fat behave. Understanding PPAR function helps explain why certain foods or medications improve metabolism for some people but not others.